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Abrupt withdrawal of zestril has not been associated with a rapid increase in blood pressure, or a significant increase in blood pressure compared to pretreatment levels.

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Information about Zestril.

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Do not use Zestril if you are pregnantIf you become pregnantstop taking this medicine and tell your doctor right awayZestril can cause injury or death to the unborn baby if you take the medicine during your second or third trimesterUse effective birth control while taking Zestril.

Zestril works by making your blood vessels widenThis helps to lower your blood pressureIt also makes it easier for your heart to pump blood to all parts of your body.

Symptomatic hypotension may occur following initiation of therapy with ZestrilThis is more likely in patients who are being treated currently with diureticsCaution is recommended thereforesince these patients may be volume and/or salt depletedIf possiblethe diuretic should be discontinued 2 to 3 days before beginning therapy with ZestrilIn hypertensive patients in whom the diuretic cannot be discontinuedtherapy with Zestril should be initiated with a 5 mg doseRenal function and serum potassium should be monitoredThe subsequent dosage of Zestril should be adjusted according to blood pressure responseIf requireddiuretic therapy may be resumedsee section 4.4 and section 4.5

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

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you should not use zestril if you have hereditary angioedema.

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