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Like other medications, you should take cozaar and diovan with care, especially pregnant women.

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A very serious allergic reaction to this drug is rareHoweverget medical help right away if you notice any symptoms of a , , , , , , , . serious allergic reactionincludingrashitching/swellingespecially of the face/tongue/throatsevere dizzinesstrouble breathing.

COZAAR 25 mg50 mg and 100 mg tablets contain potassium in the following amounts2.12 mg0.054 mEq4.24 mg0.108 mEqand 8.48 mg0.216 mEqrespectivelyCOZAAR 25 mgCOZAAR 50 mgand COZAAR 100 mg may also contain carnauba wax.

There is evidence that the concomitant use of ACE-inhibitorsangiotensin II receptor blockers or aliskiren increases the risk of hypotensionhyperkalaemiaand decreased renal functionincluding acute renal failureDual blockade of RAAS through the combined use of ACE-inhibitorsangiotensin II receptor blockers or aliskiren is therefore not recommendedsee sections 4.5 and 5.1

Losartan selectively blocks the AT 1 receptorIn vitro and in vivo losartan and its pharmacologically active carboxylic acid metabolite E-3174 block all physiologically relevant actions of angiotensin IIregardless of the source or route of its synthesis.

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