In a long-term, placebo-controlled trial in severe heart failure, patients treated with coreg had lower values for hepatic transaminases than patients treated with placebo, possibly because improvements in cardiac function induced by coreg led to less hepatic congestion and or improved hepatic blood flow.
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coreg has been evaluated for safety in subjects with heart failure mild, moderate, and severe , in subjects with left ventricular dysfunction following myocardial infarction and in hypertensive subjects the observed adverse event profile was consistent with the pharmacology of the drug and the health status of the subjects in the clinical trials.
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controlled clinical trials directly comparing coreg in doses up to 50 mg n 1,142 with placebo n 462 , 4.
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if you have heart failure or have suffered a heart attack, your doctor may prescribe coreg, or its generic equivalent carvedilol, according to the national institutes of health s medline plus website.
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